Impact of diabetes on the prognosis of hip fracture: a cohort study in the Chinese population

第一作者:WANG Hong

2013-04-01 点击量:423   我要说

WANG Hong, Lü Yan-wei, LAN Ling, ZHANG Quan, CHEN Hai-ling, ZHANG Guo-ying

DENG Li-li , LI Ju-fen

Background  Diabetes has been associated with increased risk of fracture and impaired fracture healing. The aim of this study was to examine the influence of diabetes on perioperative complications, length of stay and ambulatory ability recovery in individuals with hip fracture, and to determine whether changes could be made to improve treatment outcome.
Methods  The study included 707 hip fracture patients treated at Beijing Jishuitan Hospital between July 2009 and December 2010. The medical history and perioperative complications were compared between non-diabetic and diabetic groups. Length of stay, days awaiting surgery, and days of hospitalization after surgery were also analyzed. Ambulatory ability was compared at 1-year follow-up using the Chi-square test and Fisher’s exact test. An independent Student’s t-test was used to compare normally distributed continuous data.
Results  Patients with diabetes were more likely than non-diabetic patients to develop cardiac perioperative complications (8.9% vs. 3.0%, P=0.021), urinary tract infections (12.0% vs. 2.8%, P <0.001), and gastrointestinal symptoms (15.0% vs. 6.8%, P=0.003). No difference in perioperative complications was observed between the groups. Days awaiting surgery and length of hospital stay were both longer in the diabetic group ((8.0±5.1) vs. (6.2±3.7) days and (16.5±3.8) vs. (13.3±3.8) days, P <0.001, respectively). Before the occurrence of fracture, patients with diabetes were less likely to be ambulatory outdoors (71.9% vs. 85.9%, P <0.001) and had more restricted walking ability. After at least 1-year follow-up, similar proportions of patients in the non-diabetic and diabetic groups (16.1% and 15.9%, respectively), who were able to ambulate outdoors before the fracture, became housebound till the final follow-up.
Conclusions  Diabetics are at increased risk of specific complications and have a longer time to surgery and longer in-hospital stay, but generally have similar recovery to non-diabetics thereafter.
 

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