To the editor: Acute myocardial infarction (AMI) and acute myeloid leukemia (AML) are two intensive and life threatening diseases. Recent human studies demonstrated that C reactive protein (CRP), the best characterized biomarker of inflammation, contributed to increase cardiovascular risk1 and AML.2 Moreover, CRP could stimulate the generation of reactive oxygen species (ROS),3 which have been detected in a variety of diverse pathologic states, including atherosclerosis, and acute myeloid malignancies.4 These findings suggest that inflammatory reaction might be the identical underling pathogenesis of AMI and AML. However, most of the reported cases concerning the association of AML and AMI5 described AMI as a complication of AML. Here we report a rare case of AMI combined with AML, in which the two diseases occurred in sequence in 32 days with elevation of CRP.

Edited by WANG Mou-yue and LIU Huan