王晓楠     　王金成

    Infection is considered to be a serious complication of artificial arthroplasty. Accordingly, infection control becomes a research focus in recent years. In order to reduce its incidence, many doctors use antibiotic-loaded bone cements in primary arthroplasty, especially in those special cases, such as surgery with a long period, or with a high risk of pollution, revision surgery, and for patients with idiopathic or acquired immunodeficiency, patients with rheumatoid diseases or systemic lupus erythematosus, patients treated with radiotherapy or chemotherapy, obese patients, diabetic patients, especially patients with poor glucose control, and patients with previous joint infection or malignancy. However, there exists such problems as higher costs and a single kind of antibiotics in use. At the same time, the release time of antibiotics in bone cements is limited, which determines that the infection is mainly prevented in the introduced pathway after artificial arthroplasty. So it is uncertain whether all types of bacteria entering the human body through the introduced pathway can be included by the antibacterial spectrum of antibiotics in bone cements, and further experiments and studies are needed for doctors to verify the results. In this article, we reviewed the application of antibiotic-loaded bone cements in primary arthroplasty for reference.